CRISPR's Next Advance Is Bigger Than You Think | Jennifer Doudna | TED
Popular posts from this blog
[Research Frontier] New Trends in Prime Editing: Point Mutated Cells for Preclinical Gene Therapy
Prime editing is an improved gene editing technology based on the CRISPR/Cas system to achieve precise fragment insertion, deletion, and arbitrary substitution of bases at the target site of the genome, with higher accuracy and lower error rate. When it came out, it attracted widespread attention from many scientific researchers, and extensive research was conducted on the treatment of hereditary diseases, gene mutation diseases, and cancers. For example, correcting the mutant genes to treat genetic diseases or editing oncogenes in cancer cell genomes to prevent them from growing and spreading. The following three articles are about the clinical treatment of Prime Editing, bringing you the latest research trends. Prime editing helps in the treatment of β - thalassemia, and no off-target effect was detected β - thalassemia is a hematopoietic system disease caused by a single gene mutation in the hemoglobin (HGB) subunit beta gene (HBB), res...
CRISPR gene editing combined with magnetocaloric activation: A new strategy to assist precision medicine in cancer
In current cancer treatment, inducing tumor cell to apoptosis is a key strategy, since tumor cells gain uncontrolled proliferation ability by mechanism of inhibiting normal apoptosis. Gene editing technology, especially the CRISPR-Cas9 system, has received widespread attention due to its ability to precisely regulate the cellular functions. However, the precise control of the system in human body still faces challenges. Combined with magnetothermal therapy, its high permeability and low toxicity can be utilized to provide a new cancer treatment method by controlling the thermal effects and synergistically utilizing CRISPR-Cas9 technology. This magnetothermal - gene editing synergistic therapy demonstrates the promising therapeutic potential and provides a new strategy for precision medicine in cancer. Recently, a research paper entitled Magnetothermal activated gene editing strategy for enhanced turbine cell apoptosis, was published in Journal of Nanobiotechnology (Top of Zone 1, if: 1...
Comments
Post a Comment